Every compound we cover — what it is and where the evidence stands. Approved drugs are named as approved, animal-only evidence is named as animal-only, and popular-but-unstudied compounds are called exactly that.
evidence key — clinical = published human data · community = gray-market adoption · rated separately, on purpose
Weighing two of these against each other? See the head-to-head comparisons →
Studied for attention and working memory, recovery after brain injury or stroke and mood and stress resilience.
Studied for topical peptides for wrinkles, hair growth and skin collagen and wrinkles.
Studied for skeletal muscle glucose uptake, blood glucose in type 2 diabetes and endurance capacity.
Studied for acute rise in free fatty acids, body-fat reduction in rodents and cartilage repair in the joint.
Studied for sarcoidosis small-fibre neuropathy symptoms, corneal and skin nerve fibre regrowth and metabolic control and neuropathy in type 2 diabetes.
Studied for weight loss combined with semaglutide, weight loss beyond semaglutide alone and weight loss on its own.
Studied for raising growth hormone and IGF-1, holding the natural GH pulse pattern and muscle gain or recomposition.
Studied for muscle volume in healthy adults, walking distance in muscle disease and muscle mass in animals.
Studied for clearing senescent cells, organ function in aged animals and chemotherapy toxicity.
Studied for diabetic foot ulcer, facial wrinkles and collagen in skin.
Studied for growth hormone deficiency testing, sustained GH and IGF-I elevation and appetite and food intake.
Studied for growth hormone release, appetite stimulation and tissue protection after injury.
Studied for skin lightening, oral, skin lightening, topical and raising body glutathione stores.
Studied for diagnostic test of pituitary gonadotrophin reserve, ovulation induction in hypothalamic amenorrhoea and spermatogenesis and virilisation in hypogonadotropic hypogonadism.
Studied for growth hormone release, sustained GH release over months and growth and skinfold in short children.
Studied for neuroprotection against Alzheimer toxicity, insulin sensitivity and glucose and cognitive aging.
Studied for colitis and gut inflammation, colitis-associated tumours and bacterial and fungal killing.
Studied for raising LH and testosterone in men, raising gonadotrophins in women and testosterone in men with type 2 diabetes.
Studied for chronic weight management, type 2 diabetes glycemic control and cardiovascular risk reduction in type 2 diabetes.
Studied for bacterial killing, skin re-epithelialisation and innate host defence.
Studied for pain-free light in porphyria, skin darkening without UV and protection from sunburn.
Studied for skin darkening without UV, erections and arousal and appetite suppression.
Studied for insulin sensitivity and blood glucose, fat loss and body weight and physical performance and age-related decline.
Studied for satellite cell activation, muscle regeneration and cardiac protection after infarction.
Studied for biological-age indices in older adults, work capacity under shift work and cognitive function and memory.
Studied for low desire in premenopausal women, erections in men and desire in men.
Studied for generalised anxiety disorder, asthenia alongside anxiety and anxiety in healthy adults.
Studied for chronic weight management, type 2 diabetes glycemic control and cardiovascular risk reduction.
Studied for recovery after ischaemic stroke, optic nerve disease and motor neuron disease.
Studied for linear growth in children with growth hormone deficiency, testing whether the pituitary can secrete growth hormone and raising growth hormone and IGF-1 in older adults.
Studied for Barth syndrome, mitochondrial energy in aging muscle and healthy aging and physical function.
Studied for body-weight reduction in obesity, liver fat reduction and mASH improvement without worse fibrosis.
Studied for venous ulcer closure, neurotrophic keratopathy and severe dry eye.
Studied for visceral fat in HIV-associated lipodystrophy, visceral fat in abdominal obesity without HIV and liver fat in HIV-associated fatty liver disease.
Studied for influenza vaccine response in older adults, chronic hepatitis B and hepatitis B acute-on-chronic liver failure.
Studied for rheumatoid arthritis, age-related inflammation and tumour immunity and pain and inflammation.
Studied for chronic weight management, type 2 diabetes glycemic control and obstructive sleep apnea in obesity.
Every blurb on this page follows one rule — the evidence is described at the level it actually exists. Approved drugs are named as approved, animal-only data is named as animal-only, and thin literatures are called thin. The full grading criteria live in our editorial policy, and the companion skill is learning to read a certificate of analysis before you believe a label.